The siege of Mayyafariqin in 1259–1260 was a Mongol siege against the last Ayyubid ruler Al-Kamil Muhammad in his city of Mayyāfāriqīn (modern Silvan, Diyarbakır). The siege of Mayyāfāriqīn closely followed the 1258 siege of Baghdad and marked the beginning of the Mongol campaigns in Syria.
