2000s American LGBTQ-related comedy television series

Glee (stylized as glee) is an American jukebox musical comedy-drama television series that aired on Fox in the United States from May 19, 2009, to March 20, 2015. It focuses on the New Directions, a glee club at the fictional William McKinley High School, that is located in Ohio, USA. The club competes as a show choir while its disparate members deal with social issues, regarding sexuality, gender, race, family, teen relationships and teamwork.

Two and a Half Men is an American television sitcom created by Chuck Lorre and Lee Aronsohn that originally aired on CBS from September 22, 2003, to February 19, 2015, with a total of twelve seasons consisting of 262 episodes. Originally starring Charlie Sheen in the lead role alongside Jon Cryer and Angus T. Jones, the series was about a hedonistic jingle writer, Charlie Harper, his uptight brother, Alan, and Alan's mischievous son, Jake. As Alan's marriage falls apart and divorce appears imminent, he and Jake move into Charlie's beachfront Malibu house and complicate Charlie's freewheeling life.

Modern Family is an American television sitcom created by Christopher Lloyd and Steven Levitan. It aired on ABC from September 23, 2009, to April 8, 2020, for 11 seasons and 250 episodes. The series follows the lives of three diverse family set-ups living in suburban Los Angeles, who are interrelated through their patriarch, Jay Pritchett.

Ugly Betty is an American comedy-drama television series developed by Silvio Horta that aired on ABC from September 28, 2006, to April 14, 2010. The series is based on Fernando Gaitán's Colombian telenovela Yo soy Betty, la fea, which has had many other international adaptations. It revolves around the character Betty Suarez (America Ferrera), who – despite her lack of style – lands a job at a prestigious fashion magazine. It was produced by Silent H, Ventanarosa, and Reveille Productions partnered with ABC Studios, with Salma Hayek, Horta, Ben Silverman, Jose Tamez, and Joel Fields serving as executive producers. The pilot was filmed in New York City; seasons one and two were filmed in Los Angeles and seasons three and four were filmed in New York City.

Entourage is an American comedy-drama television series that premiered on HBO on July 18, 2004, and ended on September 11, 2011, after eight seasons. The series was created and largely written by Doug Ellin and chronicles the acting career of Vincent Chase, a young A-list movie star, and his childhood friends from Queens, New York City, as they attempt to further their nascent careers in Los Angeles.

Will & Grace is an American television sitcom created by Max Mutchnick and David Kohan. Set in New York City, the show focuses on the friendship between best friends Will Truman (Eric McCormack), a gay lawyer, and Grace Adler (Debra Messing), a straight interior designer. The show was originally broadcast on NBC from September 21, 1998, to May 18, 2006, for a total of eight seasons, and returned to NBC on September 28, 2017, and permanently ended on April 23, 2020. Will & Grace has been one of the most successful television series with gay principal characters.

Undressed is an American anthology series that aired on MTV from July 26, 1999, to September 5, 2002. The series was created and executive produced by British director Roland Joffé.

Spin City is an American sitcom television series that aired from September 17, 1996, to April 30, 2002, on ABC. Created by Gary David Goldberg and Bill Lawrence, the show is set in a fictionalized version of the New York City mayor's office, and originally starred Michael J. Fox as Mike Flaherty, the Deputy Mayor of New York. Fox departed in 2000 at the conclusion of Season 4 due to symptoms of Parkinson's disease, and Charlie Sheen became the new lead as Charlie Crawford for the final two seasons. The series was cancelled after six seasons in May 2002.

Son of the Beach is an American sitcom that aired from March 14, 2000, to October 1, 2002, on FX. The series is a spoof of Baywatch, with much of the comedy based on sexual double entendres, puns, innuendo and the like. A major running gag portrayed the handsome David Hasselhoff character as a balding, middle-aged, pot-bellied and out-of-shape man who is nonetheless seen by all the other characters as highly fit and attractive. Radio talk show host Howard Stern was one of the executive producers.

Reno 911! is an American comedy television series created by Robert Ben Garant, Thomas Lennon and Kerri Kenney-Silver for Comedy Central. It is a mockumentary-style parody of law enforcement documentary shows, specifically Cops, with comic actors playing the police officers. Lennon, Garant and Kenney-Silver all starred in and are billed as creators of the series.