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Lea Michele's second collaboration with Ryan Murphy.

Grace Phipps who will play a minor role in the series as Mandy, has appeared together alongside Skyler Samuels in The Nine Lives Of Chloe King (2011) before the show was cancelled.

This is actress Skyler Samuels second collaboration with Ryan Murphy. The first time was in American Horror Story: FreakShow in which she was a final girl/ScreamQueen. Throughout the season she encounters two serial killers Twisty the clown and Dandy Mott. She survives the killing spree & is now known as a modern day scream queen.

Coincidentally, Joe Manganiello quit Scream Queens to do Suicide Squad (2016) while Emma Roberts turned down a lead role in Suicide Squad to star in Scream Queens

Joe Manganiello dropped out of Scream Queens to star in the upcoming DC comic movie Suicide Squad (2016) and was offered the role of Deathstroke but he declined the offer.

Abigail Breslin's first televison series.

Oliver Hudson (Black Christmas) replaced Joe Manganiello after he dropped out to film Suicide Squad (2016).

Lindsay Lohan appeared in I Know Who Killed Me (2007) but isn't considered a scream queen. The movie did not do well. It's unconfirmed if she will play a role or play herself for a guest appearance on the show.

This is the second time Skyler Samuels and Emma Roberts have worked together and with Ryan Murphy. Previously they worked together on American Horror Story: Freakshow (2014).

This will the second time Lindsay Lohan and Jaime Lee Curtis will collaborate, if as rumored Lohan appears in the show. The first time was Freaky Friday (2003.)

Emma Roberts, Keke Palmer and Ariana Grande started their careers in nickelodeon TV shows. Roberts was the lead in Unfaboulous, Palmer was the star of True Jackson VP & Grande starred in Victorious. This will be the first, veteran Nick television stars will be on screen together.

This will be Emma Roberts second collaboration with Ryan Murphy

Fans have campaigned for all 90's scream queens to appear. Those include Neve Campbell, Jennifer Love Hewitt, Sarah Michelle Gellar, and even Christina Ricci.

Skyler Samuels started her career in Disney sitcom shows. Like her Costar Nick Jonas who was in the Jonas brothers band and appeared in Camp Rock. This will be the first time they will star in the same show that using for Disney.

Emma Roberts played a character in the Scream series.

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