Mississippi ( ) is a state located in the Deep South region of the United States. Mississippi is the 32nd largest and 34th-most populous of the 50 United States. Mississippi is bordered to the north by Tennessee, to the east by Alabama, to the south by the Gulf of Mexico, to the southwest by Louisiana, and to the northwest by Arkansas. Mississippi's western boundary is largely defined by the Mississippi River. Jackson is both the state's capital and largest city. Greater Jackson, with an estimated population of 580,166 in 2018, is the most populous metropolitan area in Mississippi and the 95th-most populous in the United States.