Has been in a serious relationship with Cydney Bernard since they met on the set of the movie Sommersby (1993).
Was supposed to be commencement Speaker for Smith College in Massachusetts, but eventually had to decline (2000).
Replaced Nicole Kidman in the role of "Meg Altman" in Panic Room (2002) at the last minute when Kidman injured herself.
Ranked #18 in Empire (UK) magazine's "The Top 100 Movie Stars of All Time" list (October 2007).
Her Oscar-winning role as Clarice Starling from her 1991 film The Silence of the Lambs (1991) was ranked #6 in the American Film Institute's "Heroes" list in AFI's 100 Years... 100 Heroes & Villains (2003) (TV).