Myra Bing: I don't want to belong to a church where you let a man lay dyin' while you sit here readin' your bibles.
Byron Sully: I'm good at fixin' things when I can see what's wrong. But, this thing that's comin', it's so big... I don't know where to start.
Dr. Michaela 'Mike' Quinn: We'll find a way. But I promise you, if the day ever comes that I see your heart breaking and you can't take it any longer, we'll pack up.
Preston A. Lodge III: You'll have to excuse Sully. He has a tender spot in his heart for squirrels and bunnies and such.
Hank Lawson: Bein' sheriff's a man's job, Grace.
Grace: I know. That's why I'm votin' for Matthew.
Preston A. Lodge III: What do you say, Sully? Do you think I should keep my mouth shut?
Byron Sully: I don't think it's possible, Preston.
Byron Sully: There's an old Indian legend that says man and woman were once united - four arms, four legs, two backs. And one day the great spirit grew angry at this creature and took his tomahawk and cut 'em apart. And ever since that day men and women have tried to get back together again.
Preston A. Lodge III: Why'd you do it? Why'd you save my life?
Byron Sully: If you don't know by now, you never will.
Cloud Dancing: Remember, the two-leggeds and the four-leggeds were made by the same creator. We are relatives.
Brian Cooper: I need your help. I still can't get this 'perspective' thing right.
Isabelle Maynard: You have better perspective than most people I know.
Grace: There's a sayin' - 'The devel you know is better then the devil you don't know'. Well, Hank, you're the devil we know.
(after Dr. Mike is accepted into a prestigious medical society)
Hank Lawson: And we thought she was know-it-all before this.
Byron Sully: She's awfully angry.
Cloud Dancing: You have stuck your hand in a hornet's nest that was hidden. I have done that myself.
Byron Sully: Well, if this is what it's gonna be like bein' with a woman, I don't know if I'm fit for it.
Byron Sully: Rich people pay to eat snails?
Loren Bray: Seems parents and children spend half their lives not seeing eye to eye. By the time they do find some common ground, there's barely any time left to enjoy it.
Hank Lawson: What was I thinking? I had to be crazy! Any man puts up with your harpin's gotta be looney!
Dr. Michaela 'Mike' Quinn: Any man who doesn't care about his friends isn't much of a man.
Hank Lawson: Don't worry Michaela, you're man enough for both of us.
Dr. Michaela 'Mike' Quinn: Well, I never!
Hank Lawson: Yeah, well maybe that's the problem.
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