The 1941 South Carolina Gamecocks football team was an American football team that represented the University of South Carolina in the Southern Conference (SEC) during the 1941 college football season. In their fourth season under head coach Rex Enright, the Gamecocks compiled a 4–4–1 record (4–0–1 against conference opponents), finished second in the SoCon, and were outscored by a total of 103 to 100.
