People from the Metropolitan City of Genoa

Alice D'Amato (born 7 February 2003) is an Italian artistic gymnast. She represented Italy at the 2020 and 2024 Olympic Games. Individually she is the 2024 Olympic balance beam champion. On the uneven bars she is the 2023 and 2024 European champion, the 2022 European silver medalist, and the 2019 European bronze medalist. Additionally she is a two-time European all-around medalist. She was a member of the teams that won silver at the 2024 Olympic Games, bronze at the 2019 World Championships, and gold at the 2022 and 2024 European Championships. She is the twin sister of Asia D'Amato.

Marcella Michelangeli (born 28 January 1943) is an Italian former actress and singer.

Asia D'Amato (born 7 February 2003) is an Italian artistic gymnast. She represented Italy at the 2020 Olympic Games. She was a member of the teams that won bronze at the 2019 World Championships and gold at the 2022 European Championships. Individually she is the 2021 World vault silver medalist, the 2022 European all-around champion and vault silver medalist, the 2019 and 2020 Italian national champion, and the 2018 Junior European vault champion. She is a member of the Italian National Team and is the twin sister of Alice D'Amato.

Natalino Otto, stage name of Natale Codognotto (24 December 1912 – 4 October 1969) was an Italian singer. He started the swing genre in Italy.

Enrica Antonioni (Cavi di Lavagna, Italy, 25 February 1952) born Enrica Fico, is an Italian film director and actress, the widow of Michelangelo Antonioni.

Dolly Sinatra (born Natalina Maria Vittoria Garaventa; December 26, 1896 – January 6, 1977) was the mother of American singer Frank Sinatra. She was born in Lumarzo (Province of Genoa), in northern Italy; she immigrated to the United States as an infant.

Ariadna Aleksandrovna Scriabina (Russian: Ариадна Александровна Скрябина; also Sarah Knut, née Ariadna Alexandrovna Schletzer, pseudonym Régine; 26 October 1905 – 22 July 1944) was a Russian poet and activist of the French Resistance, who co-founded the Zionist resistance group Armée Juive. She was posthumously awarded the Croix de guerre and Médaille de la Résistance.

Vincenzo Cammaroto (born April 1, 1983 in Santa Margherita Ligure) is an Italian football Defender who currently plays for Sestri Levante.

Umberto Bindi (12 May 1932 – 23 May 2002) was an Italian singer-songwriter. He is especially known for the popular song he co-wrote with Gino Paoli, Il Mio Mondo ("You're My World"), which he recorded in Italian in 1963. It was later performed by singers in English and other languages.

Susanna Fontanarossa (Ligurian: Suzanna Fontann-arossa; 1435–1489) was the mother of navigator and explorer Christopher Columbus.