People from Santa Cruz Province, Argentina

Hilda Sarah Bernard (29 October 1920 – 20 April 2022) was an Argentine actress. She had an extensive career on television, film, stage, and radio.

Néstor Carlos Kirchner Jr. (25 February 1950 – 27 October 2010) was an Argentine lawyer and politician who served as the 50th President of Argentina from 2003 to 2007, Governor of Santa Cruz Province from 1991 to 2003, Secretary General of UNASUR and the first gentleman during the first tenure of his wife, Cristina Fernández de Kirchner. He was President of the Justicialist Party from 2008 to 2010. Ideologically, he identified himself as a Peronist and a progressive, with his political approach called Kirchnerism.

Alberto Argibay (25 October 1932 – 10 September 2007) was an Argentine actor. He appeared in 51 films and television shows between 1958 and 1998. He starred in the film Circe, which was entered into the 14th Berlin International Film Festival.

Archibald S. Dobbins (1836 – circa 1869) was a Confederate cavalry commander in the American Civil War.

Daniel Román Peralta (born July 1, 1955) is an Argentine Justicialist Party politician, elected governor of Santa Cruz Province in 2007.

Alicia Margarita Kirchner (born July 18, 1946) is an Argentine Justicialist Party politician. She is the elder sister of the late former President Néstor Kirchner and served in his government as Minister of Social Development, a role which she held under President Cristina Fernández de Kirchner, her sister-in-law, until the end of her presidential term on December 9, 2015. On December 10, 2015, she was sworn in as the governor of the Province of Santa Cruz.

Jorge Fernando "Locomotora" Castro (Spanish: locomotive) (born August 18, 1967) is an Argentine boxer and former middleweight champion of the world, who is best known for his second defense of the title against John David Jackson in 1994.

Facundo Tobares (born 23 March 2000) is an Argentine professional footballer who plays as a striker for Aldosivi.

Eduardo Ariel Arnold (born October 14, 1947) is an Argentine politician. He has been vice governor of the Santa Cruz Province under Néstor Kirchner, and a national senator and deputy.

Pablo Andrés Alvarado (born 27 February 1986 in El Calafate, Santa Cruz) is an Argentine footballer who plays as a defender for Independiente del Valle.