People from Napoleonville, Louisiana

Brandon Christopher Jacobs (born July 6, 1982) is a former American football running back, who spent the majority of his career with the New York Giants of the National Football League (NFL). He was drafted by the Giants in the fourth round of the 2005 NFL Draft. He won two Super Bowl rings with the Giants, both against the New England Patriots. He also played one season for the San Francisco 49ers before returning to New York for his final season. He played college football at Coffeyville, Auburn, and Southern Illinois.

Louis Hall Nelson (September 17, 1902 – April 5, 1990) was a New Orleans jazz trombonist.

Kim Marie Willoughby (born November 7, 1980) is a retired American indoor volleyball player. She is 5'11" (1.80 m) and is an outside hitter. In 2007, she played professionally for the Italian Serie A League Familia Chieri. In April 2008, she joined the U.S. national team. Willoughby made her Olympic debut at the 2008 Beijing Olympics, helping the USA to a silver medal.

Francis Redding Tillou Nicholls (August 20, 1834 – January 4, 1912) was an American attorney, politician, judge, and a brigadier general in the Confederate States Army during the American Civil War. He served two terms as the 28th Governor of Louisiana, first from 1876 to 1880 and then from 1888 to 1892.

Oscar Phillip Celestin (January 1, 1884 – December 15, 1954) better known by stage name Papa Celestin was an American jazz trumpeter and bandleader.

Charles Joseph Melançon (born October 3, 1947) is an American politician and the former secretary of the Louisiana Department of Wildlife and Fisheries.

Risley Claiborne Charles Triche, also known as Pappy Triche (August 16, 1927 - June 26, 2012), was an attorney in Napoleonville, Louisiana, who served as a Democratic member of the Louisiana House of Representatives from 1955 to 1976. Known for his flamboyance and theatrics in political circles, Triche represented Assumption Parish during his entire legislative tenure and also Ascension Parish during his last four-year term, from 1972 to 1976.

Henry Anthony Politz (May 9, 1932 – May 25, 2002) was a United States Circuit Judge of the United States Court of Appeals for the Fifth Circuit.

Henry Hall (August 29, 1922 – May 25, 2016) was a boxer from Napoleonville, Louisiana, USA. His birth name was William Hall.

Samuel Albert LeBlanc (August 29, 1886 – July 8, 1955) was a Justice of the Louisiana Supreme Court from December 12, 1949 to December 31, 1954.