People from Assumption Parish, Louisiana

Johnny Sand Meads (born June 25, 1961 in Labadieville, Louisiana) is a former professional American football linebacker in the National Football League for the Houston Oilers from 1984–1992 and Washington Redskins in 1992. Meads was drafted in the third round of the 1984 NFL Draft by the Houston Oilers and was also a third round (56th overall) selection by the New Orleans Breakers in the 1984 USFL Draft.

Charles Joseph Melançon (born October 3, 1947) is an American politician and the former secretary of the Louisiana Department of Wildlife and Fisheries.

Risley Claiborne Charles Triche, also known as Pappy Triche (August 16, 1927 - June 26, 2012), was an attorney in Napoleonville, Louisiana, who served as a Democratic member of the Louisiana House of Representatives from 1955 to 1976. Known for his flamboyance and theatrics in political circles, Triche represented Assumption Parish during his entire legislative tenure and also Ascension Parish during his last four-year term, from 1972 to 1976.

Samuel Albert LeBlanc (August 29, 1886 – July 8, 1955) was a Justice of the Louisiana Supreme Court from December 12, 1949 to December 31, 1954.

Troy Earl Brown (born August 22, 1971) is a Democratic former member of the Louisiana State Senate. From 2012 to 2017, when he resigned his seat under duress, Brown represented District 2, which includes parts of Ascension, Assumption, Iberville, Lafourche, St. Charles, St. John the Baptist, St. James, and West Baton Rouge parishes.

William Schwing Patout, III (October 15, 1932 – August 5, 2017), was an American businessman and agricultural engineer from New Iberia, Louisiana.

Samuel Albert LeBlanc, I (August 29, 1886–July 8, 1955), was a lawyer from Napoleonville in Assumption Parish, Louisiana, who was a Democratic former member of the Louisiana House of Representatives from 1912 to 1916.

Joseph Arthur Harrison, known as Joe Harrison (born February 15, 1952), is an American financial planner from Napoleonville, Louisiana, who is a Republican former member of the Louisiana House of Representatives for District 51 in Assumption, Lafourche, St. Mary, and Terrebonne parishes. He formerly served on the board of the American Legislative Exchange Council (ALEC), a conservative group of state legislators and private businesspersons.

Jane Margaret Triche Milazzo (born March 2, 1957) is a United States District Judge of the United States District Court for the Eastern District of Louisiana.

Edwin Lawrence "Eddie" Johnson (December 11, 1920 – April 7, 2010) was an American jazz and blues tenor saxophonist. He was born in Napoleonville, Louisiana, United States.