Mass murder in Cairo

On 14 August 2013, the Egyptian police (and to a lesser extent the armed forces), under the command of then-Defense Minister Abdel Fattah el-Sisi, used lethal force to “disperse” two camps of protesters in Cairo: one at al-Nahda Square and a larger one at Rabaa al-Adawiya Square. The two sites had been occupied by supporters of President Mohamed Morsi, who had been removed from office by the military a little over a month earlier following mass protests against his rule. Initiatives to end the six-week sit-ins by peaceful means had failed, and the camps were cleared out within hours.

On 6 October 1981, Field Marshal Anwar Sadat, the 3rd President of Egypt, was assassinated during the annual victory parade held in Cairo to celebrate Operation Badr, during which the Egyptian Army had crossed the Suez Canal and taken back the Sinai Peninsula from Israel at the beginning of the Yom Kippur War. The assassination was undertaken by members of the Egyptian Islamic Jihad. Although the motive has been debated, Sadat's assassination likely stemmed from Islamists who opposed Sadat's peace initiative with Israel and the United States relating to the Camp David Accords.

On 24 and 25 January 2014 a series of bombs exploded in Greater Cairo. The first four explosions occurred on the day before the anniversary of the Egyptian Revolution of 2011, with the fifth coming on the anniversary itself.

The Maspero Massacre initially started as demonstrations in October 2011 by a group dominated by Egyptian Copts in reaction to the demolition of a church in Upper Egypt claimed to be built without the appropriate license. The peaceful protesters who intended to stage a sit-in in front of the Maspiro television building were attacked by security forces and the army, resulting in 24 deaths, mostly among the Coptic protestors, and 212 injuries, most of which were sustained by Copts.

The Cairo fire (Arabic: حريق القاهرة), also known as Black Saturday, was a series of riots that took place on 26 January 1952, marked by the burning and looting of some 750 buildings—retail shops, cafes, cinemas, hotels, restaurants, theatres, nightclubs, and the city's Casino Opera —in downtown Cairo. The direct trigger of the riots was the Battle of Ismailia, an attack on an Egyptian police installation in Ismaïlia by British forces on 25 January, in which roughly 50 auxiliary policemen were killed.

On 28 November 1971, Wasfi Tal, the 15th Prime Minister of Jordan, was assassinated while he was on his way to attend an Arab League meeting at the Sheraton Hotel in Cairo, Egypt. Tal was shot at close range by a member of the Black September Organization, which was said to be responding to the 1970 Black September conflict.

The Cairo bus attack was an attack on a bus carrying Israeli tourists in Cairo, Egypt that occurred on February 4, 1990. The assault was claimed by two groups, an unknown group calling itself the 'Organisation for the Defense of the Oppressed of Egypts Prisons' which claimed to have done it to protest the torture in Egyptian prisons, and the Palestinian Islamic Jihad. Nine Israeli civilians were killed and 17 more were wounded with automatic fire and hand grenades. The attack was the worst on Israelis in Egypt since the two countries signed a peace agreement in 1979.

On 25 February 1986 around 25,000 conscripts of the Central Security Forces (CSF), an Egyptian paramilitary force, staged violent protests in and around Cairo. The riot came as a reaction to the rumour that their three-year compulsory service would be prolonged by one additional year without any additional benefits or rank promotion.

On 11 December 2016, a suicide bomber killed 29 people and injured 47 others at St. Peter and St. Paul's Church (commonly known as El-Botroseya Church), a chapel next to Saint Mark's Coptic Orthodox Cathedral, seat of the Coptic Orthodox Pope, in Cairo's Abbasia district. Egypt's President, Abdel Fattah el-Sisi identified the bomber as 22-year-old Mahmoud Shafiq Mohammed Mustafa, who had worn a suicide vest. el-Sisi reported that three men and a woman have been arrested in connection with the attack; two others are being sought. ISIS claimed responsibility for the attack.

On December 4, 2015, a molotov cocktail was thrown into the El Sayad restaurant in Cairo, Egypt. The resultant fire killed 17 people, and wounded six. The restaurant was also a nightclub and was located in the Agouza district of the city.