Female supervillains

Black Widow (Natalia Alianovna "Natasha" Romanova; Russian: Наталья Альяновна "Наташа" Романова) is a character appearing in American comic books published by Marvel Comics. Created by editor and plotter Stan Lee, scripter Don Rico, and artist Don Heck, the character debuted in Tales of Suspense #52 (April 1964). The character was introduced as a Russian spy, an antagonist of the superhero Iron Man. She later defected to the United States, becoming an agent of the fictional spy agency S.H.I.E.L.D. and a member of the superhero team the Avengers.

Catwoman is a fictional character appearing in American comic books published by DC Comics, commonly in association with the superhero Batman. Created by Bill Finger and Bob Kane, the character made her debut as "the Cat" in Batman #1 (June 1940).

Poison Ivy (Pamela Lillian Isley () is a fictional supervillain appearing in comic books published by DC Comics, commonly in Batman stories. Poison Ivy was created by Robert Kanigher and Sheldon Moldoff, and made her debut in Batman #181 (June 1966).

Mystique (Raven Darkhölme) is a character appearing in American comic books published by Marvel Comics. Created by artist David Cockrum and writer Chris Claremont, the character first appeared in Ms. Marvel #16 (April 1978). A member of a subspecies of humanity known as mutants who are born with superhuman abilities, Mystique is a shapeshifter who can mimic the appearance and voice of any person with exquisite precision. Her natural appearance includes blue skin, red hair and yellow eyes.

Blackfire (Komand'r) is a supervillain who appears in the fictional DC Universe. She is the older sister of the Titans member Starfire and Omega Men member Ryand'r. The character first appears in New Teen Titans #22, and was created by Marv Wolfman and George Pérez.

Harley Quinn (Dr. Harleen Frances Quinzel) is a fictional character appearing in media published by DC Entertainment. The character was created by Paul Dini and Bruce Timm, and first appeared in Batman: The Animated Series in September 1992. She later appeared in DC Comics' Batman comic books, with the character's first comic book appearance in The Batman Adventures #12 (September 1993).

Caroline "Carol" Ferris is a fictional character appearing in the DC Comics Universe. She is one of many characters who has used the name Star Sapphire, and was the long-time love interest of Hal Jordan, the Silver Age Green Lantern. In her role as Star Sapphire, Ferris has been active as both a supervillain and, more recently, as a superhero. Her original design was based on Elizabeth Taylor. In the 2011 feature film Green Lantern, actress Blake Lively plays the role of Ferris. Carol Ferris was ranked 36th in Comics Buyer's Guide's "100 Sexiest Women in Comics" list.

The Black Cat (Felicia Hardy) is a fictional character, a superheroine in comic books published by Marvel Comics. Created by writer Marv Wolfman and artist Keith Pollard, she first appeared in The Amazing Spider-Man #194 (July 1979).

Callisto is a fictional character in the fantasy TV series Xena: Warrior Princess. She features as the most frequently recurring villainess on that show. She also makes appearances on three episodes of the parent show Hercules: The Legendary Journeys. She is portrayed by the American actress Hudson Leick.

Maleficent is a fictional character and the main antagonist in Walt Disney's 1959 film Sleeping Beauty. She is the self-proclaimed "Mistress of All Evil" who, after not being invited to the baby's christening, curses the infant Princess Aurora to "prick her finger on the spindle of a spinning wheel and die" before the sun sets on her sixteenth birthday. The character is Disney's adaptation of the wicked fairy godmother from the original French fairy tale.