Cross-border railway lines in Italy

The Gotthard railway (German: Gotthardbahn; Italian: Ferrovia del Gottardo), named after the Saint-Gotthard Massif which it crosses, is the Swiss trans-alpine railway line from northern Switzerland to the canton of Ticino. The line forms a major part of an important international railway link between northern and southern Europe, especially on the Rotterdam-Basel-Genoa corridor. The Gotthard Railway Company (German: Gotthardbahn-Gesellschaft) was the former private railway company that financed the construction of and originally operated that line.

The Tenda line or Cuneo-Ventimiglia line, also called in Italian: Ferrovia delle Meraviglie, 'Railway of Wonders', is a cross-border railway line in the Alpine regions of France and Italy, connecting the Maritime and Ligurian Alps. The line is 99.4 kilometres (61.8 mi) long, including an 8-kilometre (5.0 mi) tunnel under the Col de Tende mountain pass.

The Austrian Southern Railway (German: Österreichische Südbahn) is a 577.2-kilometre (358.7 mi) long double track railway, which linked the capital Vienna with Trieste, the former main seaport of Austria-Hungary, by railway for the first time. It now forms the Southern Railway in Austria and the Spielfeld-Straß–Trieste railway in Slovenia and Italy.

The Simplon Railway is a line that links Lausanne in Switzerland and Domodossola in Italy, via Brig. The 20 km (12 mi)-long Simplon Tunnel (opened in 1906) is a major part of it. The line between Lausanne and Vallorbe is sometimes considered to form part of the line, making it 233 km (145 mi) long.

The Domodossola–Locarno railway line, informally called the Centovallina in Switzerland and the Vigezzina in Italy, is a metre-gauge railway negotiating the dramatic mountainous terrain between Domodossola, Italy, and Locarno, Switzerland. It passes through the Vigezzo Valley (Italian side) and Centovalli (Swiss side).

The Marseille–Ventimiglia railway (French: Ligne de Marseille-Saint-Charles à Vintimille; Italian: Ferrovia Marsiglia-Ventimiglia) is a French-Monégasque-Italian 259-kilometre-long (161 mi) railway line. It opened in several stages between 1858 and 1872.

The Lötschberg line is a railway in Switzerland, connecting Spiez in the canton of Bern with Brig in the canton of Valais. It crosses the Bernese Alps, from the Bernese Oberland to Upper Valais, through the Lötschberg Tunnel in the middle of the line. Together with the Simplon Tunnel south of Brig, it constitutes one of the major railways through the Alps and an important north-south axis in Europe. The Lötschberg axis is backed by the lower and longer Lötschberg Base Tunnel, part of the New Railway Links through the Alps project.

The Cadenazzo–Luino railway is a railway line along the northeastern coast of Lago Maggiore. It conntects the towns of Cadenazzo and Luino, crossing the Italy–Switzerland border.

The Milano–Chiasso railway line is an Italian state-owned railway connecting Milan to Como and Chiasso, Switzerland.

The Turin–Modane railway is the international rail connection from Turin, Italy to Modane, France. It passes through the Susa Valley and the Fréjus Rail Tunnel. Together with the French Culoz–Modane railway it is often called "Fréjus Railway" or "Mont Cenis Railway". A major landslide in August 2023 forced its closure for over a year.