1569 births

Luca Matranga (Albanian: Lekë Matrënga; 18 May 1569 – 6 May 1619) was an Arbëresh writer and Catholic priest of Byzantine rite in the Albanian community of Sicily. He is regarded as one of the most important authors of Albanian literature, as his work contains the oldest written text of Albanian in the diaspora.

Handan Sultan (Ottoman Turkish: خندان سلطان, "smiling"; c. 1568 - 9 November 1605) was a consort of Ottoman Sultan Mehmed III, and mother and Valide Sultan to their son Sultan Ahmed I.

Frances Burke, Countess of Clanricarde, Dowager Countess of Essex (née Walsingham, formerly Devereux and Sidney; 1567 – 17 February 1633) was an English noblewoman. The daughter of Sir Francis Walsingham, Elizabeth I's Secretary of State, she became the wife of Sir Philip Sidney at age 16. Her second husband was Queen Elizabeth's favourite, Robert Devereaux Earl of Essex, with whom she had five children. Two years after his execution in 1601, she married Richard Burke, Earl of Clanricarde, and went to live with him in Ireland.

Emilia Lanier (also Aemilia or Amelia Lanyer, 1569–1645), née Aemilia Bassano, was an English poet and the first woman in England to assert herself as a professional poet, through her volume Salve Deus Rex Judaeorum (Hail, God, King of the Jews, 1611). Attempts have been made to equate her with Shakespeare's "Dark Lady".

Sir Robert Parkhurst (c. 1569–1636) was an English merchant who was Lord Mayor of London.

Sir Harbottle Grimston, 1st Baronet (c. 1569–1648) was an English politician who sat in the House of Commons variously between 1614 and 1648. He supported the Parliamentarian side in the English Civil War.

Heo Gyun (Korean: 허균, 3 November 1569 – 12 October 1618) was a Korean novelist, poet, and politician during the Joseon period. He was also known by his art names, Gyosan (교산) and Seongso (성소).

Antonio Marcello Barberini, OFMCap (18 November 1569 – 11 September 1646) was an Italian cardinal and the younger brother of Maffeo Barberini, later Pope Urban VIII. He is sometimes referred to as Antonio the Elder to distinguish him from his nephew Antonio Barberini.

Anna de' Medici (31 December 1569 – 19 February 1584) was the third child of Francesco I de' Medici, Grand Duke of Tuscany, and Joanna of Austria. She was a member of the famous House of Medici.

Joan Shakespeare (married name Joan Hart; baptised 15 April 1569 – buried 4 November 1646) was the sister of William Shakespeare. She is the only member of the family whose known descendants continue down to the present day.