In the novel, the lawsuit is filed against a tobacco company. This screenplay was in development for several years and, after the release of The Insider (1999), all subsequent scripts involved a lawsuit against a gun manufacturer. Although, the movie contains various references to tobacco.
'Naomi Watts (I)' was offered the role of Marlee but turned it due to scheduling conflicts.
The voice on the radio at the very beginning is Morning show host Rod Ryan. He was at one time based in New Orleans on his own show on The End. At the time the film was released on DVD, he had moved to Houston were he still broadcasts in the morning.
This is the 10th movie starring both John Cusack and Jeremy Piven.
After being in development for several years, director Alfonso Cuarón became attached to direct and co-write the film. He ended up leaving the project a few months after that.
This is Gene Hackman's and Dustin Hoffman's first film together. At the Pasadena Playhouse they were classmates and were both voted "Least Likely to Succeed".
While the notion of infiltrating a jury in the manner of Nicholas Easter is obviously intriguing, various systems exist to prevent it. For example, in most jurisdictions (including New Orelans), prospective jurors are required to have permanently resided within that jurisdiction for at least one year prior to selection.
The much anticipated bathroom scene in Runaway Jury (2003), where Rohr confronts Finch is the first ever dialog in a movie between Dustin Hoffman and Gene Hackman. It was written while the rest of the movie was being filmed, after someone on the crew found out that the two, though they had been friends since 1956, had never starred in a movie together. It was finally shot on a single day at the very end, weeks after both Hackman and Hoffman had finished their other work.
This is the second time the actors Rachel Weisz, Leland Orser, Luis Guzmán & Dustin Hoffman have starred in a movie together - the first being the movie "Confidence", also in 2003.
Joel Schumacher was originally attached to direct, largely at the insistence of John Grisham. The author had been pleased with the way Schumacher had handled two of his properties - A Time to Kill (1996) and The Client (1994).
In 1997, Edward Norton was originally cast in the role of Nicholas Easter with Joel Schumacher directing. Sean Connery and Gwyneth Paltrow were cast in the roles of Fitch and Marlee, respectively. But when Schumacher dropped out of the project and it was delayed, the actors moved on to other projects. The project was revived in 2001 when Will Smith was in talks to play Nicholas Easter with Jennifer Connelly as Marlee and Mike Newell directing. But Smith dropped out and the project was again stalled.
Naomi Watts was offered the role of Marlee but turned it due to scheduling conflicts.
In Runaway Jury the goth alternate juror who replaces the alcoholic juror who is dismissed is named Lydia Deets (played by Corri English). This is the name of the goth character Lydia Deetz in Beetle Juice, the teen who communicates with the deceased previous owners of the house (played by Winona Ryder).
Other notable actresses auditioning for the role of Marlee included Bridget Moynahan and Amanda Peet.
TheGameTrader is an actual store in the Espalanade Mall right outside of New Orleans.