Of Mice and Men is a 1992 film based on John Steinbeck's novella of the same name. Directed and produced by Gary Sinise, the film features Sinise as George Milton alongside John Malkovich as Lennie Small, Casey Siemaszko as Curley, John Terry as Slim, Ray Walston as Candy, Joe Morton as Crooks, and Sherilyn Fenn as Curley's wife. Horton Foote adapted the story for film. Wikipedia
George: Guys like us that work on ranches are the loneliest guys in the world. They ain't got no family and they don't belong no place. They got nothin' to look ahead to...
Lennie: But not us George. Tell about us.
George: ...well, we ain't like that. We got a future. We got somebody to talk to that gives a damn about us. If them other guys gets in jail they can rot for all anybody cares.
Lennie: But not us, George, because I... see, I got you to look after me, but you got me to look after you.