Mister Ed is an American television situation comedy produced by Filmways that first aired in syndication from January 5 to July 2, 1961, and then on CBS from October 1, 1961, to February 6, 1966. The show's title character is a talking horse, originally appearing in short stories by Walter R. Brooks. Wikipedia
(opening line of each episode)
Mister Ed: Hello, I'm Mr. Ed.