I Am Legend is a 2007 American post-apocalyptic science fiction horror film directed by Francis Lawrence and starring Will Smith. It is the third feature film adaptation of Richard Matheson's 1954 novel of the same name, following 1964's The Last Man on Earth and 1971's The Omega Man. Smith plays virologist Robert Neville, who is immune to a man-made virus originally created to cure cancer. He works to create a remedy while defending himself against the virus' victims, who turn into hostile mutants. Wikipedia
Anna: The world is quieter now. We just have to listen. If we listen, we can hear God's plan. Neville: God's plan. Anna: Yeah. Neville: All right, let me tell you about your "God's plan". Seven billion people on Earth when the infection hit. KV had a ninety-percent kill rate, that's five point four billion people dead. Crashed and bled out. Dead. Less than one-percent immunity. That left twelve million healthy people, like you, me, and Ethan. The other five hundred and eighty-eight million turned into your dark seekers, and then they got hungry and they killed and fed on everybody. Everybody! Every *single* person that you or I has ever known is dead! Dead! There is no god!