Family Ties is an American sitcom that aired on NBC from September 22, 1982 until May 14, 1989. The series, created by Gary David Goldberg, reflected the move in the United States from the cultural liberalism of the 1960s and 1970s to the conservatism of the 1980s. This was particularly expressed through the relationship between young Republican Alex P. Keaton (Michael J. Fox) and his ex-hippie parents, Steven and Elyse Keaton (Michael Gross and Meredith Baxter). Wikipedia
(Uncle Ned is an alcoholic)
Alex P. Keaton: You just drank a whole bottle of vanilla extract.
Ned Donnelly: I'm sorry; did you want some?